Tag: ella 1

Idaho Pharmacist Refused to Dispense Planned Parenthood Prescription Cleared of Wrongdoing

~ Pharmer

Planned Parenthood continues its harassment of an Idaho Pharmacist who refused to dispense an order for methergine, nor give a referral.

The media, acting as mouthpiece for Planned Parenthood’s version of the story gives the following outline.

The pharmacist took a call from planned parenthood about an order for methergine (which is used to stem bleeding after delivery, miscarriage, abortion). The pharmacist is said to have asked if this was related to an abortion procedure. The planned parenthood nurse would not answer, citing the privacy of the patient.
The pharmacist allegedly refused to take the order, and also did not refer the nurse to another pharmacy. She is said to have hung up the phone on planned parenthood.  (smile). And ask yourself why planned parenthood is doing abortions without this hemostatic drug on the premises. Isn’t that dangerous?

We do not have the pharmacist’s version of the story. We do have the people at Second Hand Smoke weighing in on this case, and pondering whether the pharmacist did the right thing, and was within the scope of Idaho pharmacy practice standards. As many of them had insufficient data and background to address this topic,  Pharmer was only too happy to assist them in their cogitations as follows:

Someone thinks that oral methergine is going to sufficiently address the kind of uncontrolled bleeding that can kill a patient in minutes.

Another person thinks that pharmacists should not have the patient’s medical history.

Without information as to what is being treated, the pharmacist can’t check the safety and appropriateness of the prescription. Under these conditions, the prescription should not be filled.

There are some people who should avoid health care practice due to incompetence.

At my place of employment I correct numerous physician orders each shift. This is a necessary part of my job function as a pharmacist. I also tell the physicians and nurses how to use the meds (to avoid these errors). When I was a retail pharmacist, I obtained changes in prescriptions on a regular basis. I refused to fill some prescriptions due to dangerous drug interactions, etc. I refused to stock and dispense Redux, which is now off the market, because I knew better than the FDA, at the time, that taking this drug was not worth the risk.

The pharmacist in this case was correct to refuse a prescription from a prescriber who was unwilling to verify that the prescription was within the scope of his or her practice. Pharmacists need that information to know if the prescription is legitimate and “legal to dispense”. In addition, prescriptions from Planned Parenthood should be scrutinized to see if they really have been authorized by a licensed prescriber. It appears from the story that the Planned Parenthood agent was not being cooperative with respect to providing information relevant to the prescription, and the pharmacist may have had good legal and clinical reason to avoid taking the order. Not much is really known about this case since the info is coming mainly from planned parenthood, and its media mouthpiece.

If a woman came to me AFTER the fact with a prescription for methergine, I would fill it, (and have done that in retail practice). At that time, the drug is not a part of the abortion procedure.

I would not fill a prescription which could be preliminary or a part of the actual abortion regimen.

With the availability of Ella, (ulipristal acetate) which operates in the same way as RU-486- (mifepristone), there will be many related conundrums for hospitals which don’t normally do abortions. Ulipristal at 0.5mg/kg is used as a morning after pill. The doses can be combined to use for later chemical abortions. Expect many “miscarraiges”, “missed ABs”, D&Cs to be followed up at legitimate hospitals after the woman has used ulipristal to kill her baby in the embryonic stage of development. This is a significant reason for bringing Ella to market as a morning after pill: to allow its “off label” use and finish up chemical abortions at legitimate facilities, thus dodging much of the stigma and personal $ cost associated with abortion. It is also a means to deal with the decreasing supply of abortionists.

The Idaho board has ruled that the pharmacist broke no state laws in alleged refusal to fill the prescription.

Planned Parenthood continues to harass the pharmacist by threatening to file a complaint with federal agencies.  This  is not likely to go anywhere, as this part of pharmacy practice is governed by state law.

Planned Parenthood also stuck its nose in the business of  the Pharmer  by intervening in an employment issue in which it had no legal standing.  This organization has a long history of using your tax money  (which accounts for at least a third of its income) to harass pro-life health care professionals in many different states.

Planned Parenthood has, for many years been involved in canvassing operations to locate pro-life pharmacists.  Pharmer has  received calls  to this end, and told the callers to do their own research.   Planned parenthood has sent people to “sting” CPCs and pro-life health care professionals.   For us, there is poetic justice in seeing the work of LiveAction.org, and seeing it reveal publicly  what we’ve heard all along from their dissatisfied clientele.

*Compare the Planned Parenthood complaint to the Idaho Pharmacy Board with the media feed on this issue.    Hook- Line and Sinker.

FDA remembers the old days, when it used to do its job.

~ Pharmer

Dr. Gerard M. Nadal appropriately nails the non-functional FDA to the wall, noting it’s new Kelsey award, honoring a former FDA reviewer from back when the agency was worth something.

Frances O. Kelsey, now 96 years old, is the namesake and first recipient of the Kelsey award from the FDA for doing what she was supposed to do. She stopped distribution of Thalidomide, for morning sickness, in the USA, likely sparing countless kids the associated birth defect called phocomelia, severely shortened limbs.

Nadal notes that the present FDA commissioner, Margaret Hamburg has ushered in the new drug Ella, ulipristal acetate, without appropriate testing, and with next to zero study of its effects on the babies who survive its embryocidal effects. In addition, the FDA has misbranded this drug as a contraceptive, thus disrespecting female patients’ right of informed consent to treatment.

NPR: Lost in the Weeds (As Usual) on EllaOne

~ Pharmer

NPR demonstrates why its listenership is really low and it needs public support to survive.

New ‘Morning After’ Pill Works Five Days Later, Too : NPR.

“Paul Fine would like to stop seeing emergency contraceptives referred to as “morning after pills”, the story opens.

Well, those interested in accuracy and honesty continue to use that term, since calling it “contraception” is misbranding.

All of the morning after pills can operate by interceptive  (post fertilization) mechanisms to stop the life of an early human embryo.

Not withstanding the similar words from Dr. Donna Harrison, a representative of the ob-gyn physicians who DON’T make money by prescribing these morning after pills,  NPR plods on with the latest apologetics.

The interceptive mechanisms are explained away by stating that the pills sometimes don’t work and claiming that the failures are post ovulatory.    It is fact that both Plan B and EllaOne have extremely high failure rate,  but this is not adequate evidence against  the action of interceptive mechanisms, the likelihood of which the manufacturer admits in the CHMP Assessment Report.

In fact, the interceptive mechanism of EllaOne, a drug closely related to mifepristone (RU-486) is much more obvious.   Efficacy of the drug in stopping pregnancy stays the same, (or perhaps even rises)  when used during the entire recommended 5 day period after intercourse.

The morning after pill dose is about 0.5mg/kg in an average size woman.  This is considerably LOWER  than the dose required to stop ovulation  (seen in animal studies).  This latter dose is  closer to the embryocidal, or fetocidal dose.

Think of it this way:

ulipristal acetate 30mg EllaOne morning after pill   ———-> ulipristal acetate 120mg higher dose needed  to stop ovulation——–>ulipristal acetate 300mg higher dose to kill more developed  embryos and fetuses.

Therefore, doses  of  EllaOne can be accumulated for home abortions, and one can be certain that this will happen when this morning after pill is placed over the counter.

It will become  another tool  in the armory of planned parenthood  along-side the tele-abortions offered  (in Iowa)  using mifepristone and misoprostil.

Below are tidbits from the CHMP Assessment Report,  (European Medicines Agency Evaluation of Medicines for Human Use)
which is linked here, and on the sidebar of this blog.  

1) “Ulipristal acetate (17α-Acetoxy-11β-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione, also known as CDB-2914, VA2914, HRP-2000 and RTI-3021-012) is a compound that is derived from 19-norprogesterone. It is a synthetic selective progesterone receptor modulator with antagonistic and partial agonistic effects at the progesterone receptor. It binds the human progesterone, but not the estrogen receptor3. Ulipristal acetate prevents progesterone from occupying its receptor, thus the gene transcription normally turned on by progesterone is blocked, and the proteins necessary to begin and maintain pregnancy are not synthesized.”

2) “In vitro, Ulipristal acetate binds competitively to the progesterone, glucocorticoid and androgen receptors, but has minimal affinity for the estrogen or mineralocorticoid receptors. Pre-clinical studies indicate that ulipristal acetate binds to the human progesterone, glucocorticoid and androgen receptors at approximately 6, 1.5 and 0.2 times the affinity of the endogenous ligands. The compound has antiprogestational activity in rats, rabbits and monkeys, with additional antiglucocorticoid and antiandrogen activity at doses ∼50 times higher than those needed for antiprogestational activity. Since progesterone is critical for implantation, it was thought that ulipristal acetate may have promise as a contraceptive agent.”  **

3)”The ability of ulipristal acetate to terminate pregnancies was investigated in the guinea-pig and monkey. Ulipristal, mifepristone and lilopristone were approximately equipotent at the dose levels of 10 and 30 mg/day in terminating pregnancies in guinea-pigs when the animals were treated on days 43 and 44 of gestation. Pregnant long-tailed macaques (5/group) were administered ulipristal acetate 0.5 or 5 mg/kg/day p.o. or 0.5 mg/kg/day i.m. on days 23-26 of gestation. Pregnant animals were assessed by ultrasound pretreatment (day 23) and then monitored on days 26-28, 30, 32, 35, 55, 80, 100, 130  and 145. At 0.5 mg/kg of ulipristal acetate there was no loss of foetuses, while at 5 mg/kg 2/5 foetuses were lost. When using intramuscular administration of 0.5 mg/kg 4/5 foetuses were lost in ulipristal acetate treated animals. In monkeys in which pregnancy continued and which were allowed to deliver normally, there was no evidence of structural or physiological abnormalities in foetuses.”

** note misuse of the word “contraceptive” for interceptive mechanism in tidbit number 2.

 

BOGUS Medical News: Novel ‘Morning-After’ Pill Works for Five Days – in OB/Gyn, Pregnancy from MedPage Today

~ Pharmer

Medical News: Novel ‘Morning-After’ Pill Works for Five Days – in OB/Gyn, Pregnancy from MedPage Today

More ineffective birth control is being marketed to women in Europe. This new morning after pill, Ella One, containing ulipristal 30mg, is said to be useful for up to 120 hours (5 days) AFTER intercourse.

The study (1241 women) mentioned in this article indicates that ulipristal reduces the pregnancy rate from the expected 5.5 percent down to 2.1 percent.

In this study, the women who used the pill later after intercourse had lower pregnancy rates than the earlier users, though the differences among the groups were not statistically significant. If a larger study were to replicate this trend within statistical significance it would add more evidence for the pill’s post fertilization effects. Those who understand the reproductive processes find it intuitively obvious that pills reducing pregnancy rate AFTER intercourse work to a significant degree by killing the embryo shortly after it is formed.

That ethical problem aside, women should be aware that a pill reducing the pregnancy rate from 5.5 percent to 2.1 percent should not be considered reliable.

The data here indicates that it fails to stop nearly 40 percent of the pregnancies, under study conditions with more education and oversight than usual circumstances.

*** ulipristal  ellaone ella-one  ella one sprm ella 1  ella1