What Your Pharmacist Doesn’t Know about Plan B

The folks at a major healthcare professional  education provider were scooped by Mother Jones and, prior to that, by yours truly, regarding the ineffectiveness of Plan B ONE-STEP for the bigger girls.

They had to update their not so good analysis of the morning after pills and …. it’s still not so good. If they were offering compensation, yours truly would tell them more, but this example is blogged to illustrate a single point. The public should know that their busy health care professionals are treated like mushrooms: kept in the dark and fed B.S. concerning birth control in general.

 Pharmacists have to think about a concept of steady state when asked by physicians to dose antibiotics and other drugs, or if they work in the field of drug development. Steady state is the condition during which the intake of a drug is in a sort of equilibrium with the output or the elimination of the drug. This assumes regular dosing of the drug. Steady state generally occurs after several doses and after about 5 times the half life of the drug. Ideally drug levels at steady state are high enough to be effective, and low enough to be ‘non-toxic’.

Casting about for the reason why Plan B ONE STEP doesn’t work in American women of average size or greater, the team at this Professional Education Provider, led by N B O’ Pharm.D., BCPS,wrote the following:

“The exact mechanism for the reduced efficacy seen in overweight and obese women using levonorgestrel is not known. One proposed mechanism is that in women with an increased BMI, there is a delay in time to steady state and a prolonged half-life as seen in studies with combined oral contraceptives.21″

This nonsensically applied  idea was blamed on the article below, which covered birth control hormones in general, and addressed the drugs that females take orally every day, or those which continuously supply hormone(s) to the body,  such as patches and depot injections.

Edelman AB, Cherala G, Stanczyk FZ. Metabolism and pharmacokinetics of contraceptive steroids in obese women: a review. Contraception 2010;82:314-23.

Some poor PharmD educator is talking about STEADY STATE with respect to a drug which is taken in a single dose : Plan B ONE STEP!! 

Steady State Never Happens with a single such dose!

This is just a single example but it illustrates the point.

 1) Most of your health care professionals are generally lost in the weeds regarding birth control, and don’t know what they’re talking about. That includes the ones who really SHOULD know what they’re talking about.

 Bonus) Be assured that birth control generally does not work as well in real life as the studies claim, and many factors contribute to this.

Please consider adjusting life style and reproductive planning with at least these two facts in mind.

 

Party Drug Mephedrone Unsells Itself in the UK

Mephedrone is one name for 4-Methylmethcathinone, which is related to the class of synthetic cathinone analogs known as bath salts.  These were discussed elsewhere on the Pharm, in relation to serious behavioral disturbance.

Another such story has popped up in the news. This case illustrates the propensity of mephedrone to  to lower the natural inhibitions with respect to self surgery, (in this case as chopadicktomy), and unauthorized surgery on others (stabbing).

A 19 year old student, From Haywards Heath, West Sussex,  while high on mephedrone, stabbed his 46 year old mother, giving her life threatening injuries, then cut off his own penis. An individual close to the family told the Daily Mirror that the 19 year old “is normally a lovely lad, and very bright.  But unfortunately, he had started dabbling in drugs”

Don’t do Mephedrone.

Supreme Court Justice Delays HHS Mandate

The Little Sisters of the Poor who run a Home for the Aged in Denver,  requested an emergency stay of the HHS mandate, forcing religious organizations to pay for birth control / sterilization / abortion.  After a federal appeals court failed to respond, Supreme Court Justice Sonia Sotomayor decided late on New Years Eve to block this requirement of Obamacare.  Government officials have until 10am Friday morning to respond.

Sotomayor’s decision excuses the religious organizations from being forced to comply with the birth control / abortion / sterilization mandate while the Supreme Court addresses the issue.

A&E Preaches Tolerance After It Displayed the Opposite.

The monetary cost was just too high for A&E to persist in its leftist intolerance, so with a hypocritical sermon to the rest of us about “unity, tolerance and acceptance”, the network agreed that Phil Robertson would remain on the Duck Dynasty Series.

After A&E tried to boot out a man who practices all three of their supposed values better than they do, they’re now telling us how to live, and what to think.  Objection to specific activities is entirely different from the intolerance that the leftists practice, in trying to destroy the lives of everyone who has opposing opinions and practices. Ask the bakers and the photographers who have lost their livelihoods because they opposed the practice of gay marriage on religious grounds, or health care professionals who have lost their jobs for opposing abortion.  Less famous people than Phil are routinely being squashed by leftist intolerance.

A&E has no values which they hold as more important than money. They fear losing that more than anything, and this was clearly demonstrated for all to see. The same can be said for Cracker Barrel.  The question for the future is whether you want to support organizations which will throw you and your kind overboard at the first possible opportunity.  It is possible for you to obtain Duck Dynasty episodes without having cable television.  Buy the series alone from Amazon and stream it through a Roku box.  You might be paying for cable only to watch a very few shows.  Cut the cable and use the internet.  As for Cracker Barrel….. that company appears to be past its prime, now that people understand the nature of its management.

Please consider redirecting your funds away from those who seek to silence you, or remove you from society altogether.

Not as bad off as Americans being probed by law enforcement

Nearly 30 Men Receive Some of the Worst News Possible Following Invasive Medical Exams | Video | TheBlaze.com.

About 30 patients got bad news from Seattle’s Swedish Medical Center after errors in the sterilization process of their ultrasound probes.  Twenty seven men who had prostate exams this past fall got letters from the center, suggesting that they undergo testing for Hepatitis B and C, as well as HIV.

Pharmer thinks that those patients are not facing as serious a risk as those Americans who are being probed on the side of the road, or at airports by “officials” who don’t wash their hands or change gloves between gropings.

Comprehensive Review of Planned Parenthood Pill Scam

…….. is available at Jill Stanek’s blog.

After years of planned parenthood pushing the morning after pill, they have turned on Plan B One-step, admitting what Pharmer has been saying for years,  that it’s very ineffective.

What Jill Stanek points out is that Planned Parenthood already had a campaign lined up to push Ella (ulipristal acetate) analog of the mifepristone abortion pill, as the new morning after pill, and an IUD, which could bring them even more cash than their  abortion procedures do.  This campaign was already in the pipeline BEFORE Mother Jones spilled the story of Plan B’s ineffectiveness to the low information crowd.  Note that the video linked above was already uploaded on September 3, 2013, prior to the Mother Jones publication.  Anne Glasier’s study of Plan B inefficacy in women was published in 2011.

Back in 2010, Pharmer brought to your attention the CHMP assessment report, filed by the manufacturer of Ella One to  Europe’s version of the FDA. and explained some of the features of the pill.   Initially mentioned was that Ella One, which is called Ella in the U.S. is not very effective, and that the embryocidal dose of the pill is lower than the dose required to stop ovulation, demonstrated in the animal trials.   Also from this report, is the information that the 30mg dose is designed for 60 kg (132 lb) women, is designed to deliver  the 0.5mg/kg dose which the manufacturer stated  to be insufficient to stop ovulation, but effective against pregnancy.  This dose is not sufficient for larger women, and so Ella has  similar efficacy problems as the various forms of Plan B and Plan B One-Step (levonorgestrel).

Expect planned parenthood to sell Ella as long as it can get away with it, then kick the morning after use  aside, as women are persuaded to wear the indwelling coat hanger, Para-Gard, a copper IUD.   Pharmer thinks that planned parenthood will always keep Ella around generically, since it can be substituted for the mifepristone now marketed in the U.S. for chemical abortions.

The HPV Vaccine Lacks Reproductive Safety Studies in Females

Dr Dierdre Little of Australia hunted for reproductive safety studies of the HPV vaccine after one of her teen patients experienced premature menopause. She found out that the drug developer did not bother, and the FDA did not require such studies.  She has also found insufficient  followup evaluation of this drug.
Japan has dropped support for this vaccine. India is citing lack of sufficient safety studies for the vaccine, and the feminist groups there are opposing it’s use.
This video is definitely worth a look. Click HERE

Dr Diedre Little presents Gardasil Safety Studies
Dr Diedre Little presents Gardasil Safety Studies

Chinese Meta-analysis Reveals Stronger Abortion-Breast Cancer Link Than US Studies

Check out A meta-analysis of the association between induced abortion and breast cancer risk among Chinese females by Yubei Huang, Xiaoliang Zhang,Weiqin Li, Fengju Song,Hongji Dai,Jing Wang,Ying Gao,Xueou Liu,Chuan Chen,Ye Yan, in the Journal, Cancer Causes and Control.
This study shows a strong association between abortion and breast cancer, with the risk starting at 44% increase, and escalating further with each successive abortion.

Dr Joel Brind who did a similar analysis in the U.S. explains the Chinese research further. Click HERE to read.

Obama Administration Revving Up for Christmas

The first Christmas Present from Obama is to delay the Obamacare Mandate for Small businesses (unilaterally, without an act of Congress) so that fewer people will find out how much his health-kill plan sux until after the 2014 elections.  The other reason for the delay is that these incompetents could not get the website up and running in time to implement the requirements of the law as it was written.  The delayed, Dec 1 deadline also can’t be met.  This should increase your longing for  a totally socialized system, with the current administration of idiots running it.

visit thepeoplescube.com
Obama Evil Santa from The People’s Cube

You can head to The People’s Cube to find out the 12 burdens of Obamacare that SantObama has for us… in a parody of the classic song.

Evil SantObama’s IRS  is now auditing a cancer patient who dared to tell Fox news that his insurance policy had been cancelled because of Obamacare.  The man’s luck changed when  insurance company subsequently found a way for him to keep a policy, but the IRS is going to audit his 2009 books and punish an insurance broker, who dared to lend him assistance, with an audit back to 2003.

visit http://theloonkingspoon.com
Take your Medicine -The Looking Spoon

The message is that you are to keep silent while Obama screws your life away.